Ondansetron and teratogenicity in rats: Evidence for a mechanism mediated via embryonic hERG blockade.
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DOI: 10.1016/j.reprotox.2018.08.018
Abstract: The potent hERG channel blocking drug ondansetron is used off-label for treatment of nausea and vomiting in early pregnancy. Some human epidemiological studies have associated ondansetron with fetal cardiovascular defects and orofacial clefts. This study… read more here.
Keywords: mediated via; herg; ondansetron; ondansetron teratogenicity ... See more keywords