MRI features of pediatric atypical teratoid rhabdoid tumors and medulloblastomas of the posterior fossa
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DOI: 10.1002/cam4.5780
Abstract: Atypical teratoid rhabdoid tumor (AT/RT) occurs at a younger age and is associated with a worse prognosis than medulloblastoma; however, these two tumor entities are mostly indistinguishable on neuroimaging. The aim of our study was… read more here.
Keywords: mri features; atypical teratoid; teratoid rhabdoid;
Neoadjuvant chemotherapy for atypical teratoid rhabdoid tumors (AT/RTs)
Sign Up to like & getrecommendations! Published in 2019 at "Child's Nervous System"
DOI: 10.1007/s00381-019-04422-7
Abstract: Purpose Atypical teratoid rhabdoid tumor (AT/RT) is a rare, clinically highly malignant tumor. The extent of the surgical resection may affect survival. However, it is often difficult to perform gross total resection (GTR) at an… read more here.
Keywords: chemotherapy; teratoid rhabdoid; atypical teratoid; neoadjuvant chemotherapy ... See more keywords
Atypical teratoid/rhabdoid tumor in adults: a systematic review of the literature with meta-analysis and additional reports of 4 cases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-022-03959-z
Abstract: Atypical teratoid/rhabdoid tumor (AT/RT) is a highly aggressive embryonal CNS neoplasm, characterized by inactivation of SMARCB1 (INI1) or rarely of SMARCA4 (BRG1). While it is predominantly a childhood tumor, AT/RT is rare in adults. We… read more here.
Keywords: tumor; review; atypical teratoid; teratoid rhabdoid ... See more keywords
Identification of Hub Genes in Atypical Teratoid/Rhabdoid Tumor by Bioinformatics Analyses
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DOI: 10.1007/s12031-020-01587-8
Abstract: Atypical teratoid/rhabdoid tumor (ATRT) is a devastating intracranial tumor in children. Currently, its molecular mechanisms cannot be studied effectively because patient samples are limited, and many factors are involved in its pathogenesis. In this study,… read more here.
Keywords: rhabdoid tumor; teratoid rhabdoid; atypical teratoid; hub genes ... See more keywords
Drug screening with a novel tumor-derived cell line identified alternative therapeutic options for patients with atypical teratoid/rhabdoid tumor
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DOI: 10.1007/s13577-020-00438-3
Abstract: Atypical teratoid/rhabdoid tumor (AT/RT) is a rare intracranial tumor occurring predominantly in young children. The prognosis is poor, and no effective treatment is currently available. To develop novel effective therapies, there is a need for… read more here.
Keywords: teratoid rhabdoid; cell line; atypical teratoid; cell ... See more keywords
Disulfiram potentiates the anticancer effect of cisplatin in atypical teratoid/rhabdoid tumors (AT/RT).
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.05.006
Abstract: Atypical teratoid/rhabdoid tumor (AT/RT) is the most malignant tumor of the central nervous system that generally occurs in young children. Despite the use of intensive multimodal therapy for AT/RT, the prognosis is still poor. The… read more here.
Keywords: combination; teratoid rhabdoid; atypical teratoid; cisplatin ... See more keywords
Does Stereotactic Radiosurgery Positively Impact the Local Control of Atypical Teratoid Rhabdoid Tumors?
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DOI: 10.1016/j.wneu.2017.04.132
Abstract: BACKGROUND Atypical teratoid rhabdoid tumors (ATRTs) are rare and aggressive tumors, usually affecting patients younger than 3 years of age, that are characterized by a poor prognosis. Nowadays multimodal management, including surgery, chemotherapy and radiation… read more here.
Keywords: rhabdoid tumors; teratoid rhabdoid; atypical teratoid; management ... See more keywords
Paediatric atypical teratoid/rhabdoid tumour of the pineal region mimicking a meningioma: a case report and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of neurosurgery"
DOI: 10.1080/02688697.2021.1895971
Abstract: PURPOSE Atypical teratoid/rhabdoid tumour (AT/RT) is a highly malignant central nervous system tumour of early childhood. According to the latest WHO classification, the diagnosis of AT/RTs needs to be confirmed by the absence of SMARCB1… read more here.
Keywords: teratoid rhabdoid; pineal region; atypical teratoid; case ... See more keywords
Advancing biology based therapeutic approaches for atypical teratoid rhabdoid tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa046
Abstract: Atypical teratoid rhabdoid tumor (ATRT) is a rare, highly malignant central nervous system cancer arising in infants and younger children, historically considered to be homogenous, monogenic and incurable. Recent use of intensified therapies has modestly… read more here.
Keywords: teratoid rhabdoid; biology based; atypical teratoid; advancing biology ... See more keywords
ATRT-22. HIGH-THROUGHPUT DRUG SCREENING OF FDA-APPROVED CANCER DRUGS REVEALS POTENTIAL THERAPEUTIC APPROACHES FOR ATYPICAL TERATOID RHABDOID TUMOUR
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DOI: 10.1093/neuonc/noaa222.021
Abstract: Abstract Atypical teratoid/rhabdoid tumors (ATRT), are the most common brain tumor in children under the age of 1 year with an overall survival of ~17%. Like extracranial rhabdoid tumors, ATRT is exclusively characterized by bi-allelic… read more here.
Keywords: throughput drug; teratoid rhabdoid; atypical teratoid; drug screening ... See more keywords
The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-Oncology"
DOI: 10.1093/neuonc/nox067
Abstract: Background Atypical teratoid/rhabdoid tumors (AT/RTs) are deadly pediatric brain tumors driven by LIN28. Mammalian target of rapamycin (mTOR) is activated in many deadly, drug-resistant cancers and governs important cellular functions such as metabolism and survival.… read more here.
Keywords: teratoid rhabdoid; atypical teratoid; tak228; mtor ... See more keywords