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   Articles with "terc" as a keyword



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Structural modeling of a novel TERC variant in a patient with aplastic anemia and short telomeres

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recommendations! Published in 2018 at "Annals of Hematology"

DOI: 10.1007/s00277-018-3415-5

Abstract: Dear Editor, Inherited bone marrow failure syndromes (IBMFS) are a heterogeneous group of genetic blood disorders in which there is usually some form of aplastic anemia, associatedwith a family history of the same disorder. In… read more here.

Keywords: aplastic anemia; anemia; terc variant; terc ... See more keywords
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Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease

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recommendations! Published in 2017 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2016.12.017

Abstract: &NA; Studies investigating telomere length in association with cognitive decline, dementia, and sporadic Alzheimer's disease (AD) have frequently found shorter telomeres to be associated with the development of AD and telomerase expression with pathological processes… read more here.

Keywords: telomerase; susceptibility; common variants; telomere length ... See more keywords
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HuR regulates telomerase activity through TERC methylation

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recommendations! Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-04617-7

Abstract: Telomerase consists of the catalytic protein TERT and the RNA TERC. Mutations in TERC are linked to human diseases, but the underlying mechanisms are poorly understood. Here we report that the RNA-binding protein HuR associates… read more here.

Keywords: methylation; telomerase activity; hur regulates; terc ... See more keywords
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Urinary Exosomal Long Noncoding RNA TERC as a Noninvasive Diagnostic and Prognostic Biomarker for Bladder Urothelial Carcinoma

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recommendations! Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/9038808

Abstract: Purpose Bladder cancer is one of the most common urological malignancies worldwide, and approximately 90% of bladder cancer cases are histologically typed as bladder urothelial carcinoma (BLCA). Exosomes are 30 to 200 nm extracellular vesicles that… read more here.

Keywords: bladder urothelial; prognostic biomarker; terc; urinary exosomal ... See more keywords
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Genomic amplification of HPV, h-TERC and c-MYC in liquid-based cytological specimens for screening of cervical intraepithelial neoplasia and cancer

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recommendations! Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2018.9825

Abstract: Cervical cancer is one of the most prevalent female cancer types in developing countries. ThinPrep cytological test (TCT) and human papillomavirus (HPV) detection are canonical screening methods for cervical cancer currently. However, there are limitations… read more here.

Keywords: histopathology; screening cervical; terc; hpv ... See more keywords