Biosimilarity Assessment of the Biosimilar Teriparatide Candidate and the Reference Drug in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1221
Abstract: SAL001, a recombinant form of parathyroid hormone, is a biosimilar drug to teriparatide and is planned to be used in osteoporosis treatment. A single‐dose, randomized, open‐label, 2‐way crossover trial was conducted in healthy subjects to… read more here.
Keywords: reference drug; reference; concentration; teriparatide ... See more keywords
Teriparatide and bisphosphonate use in osteoporotic spinal fusion patients: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Osteoporosis"
DOI: 10.1007/s11657-020-00738-z
Abstract: Purpose Osteoporosis is one of the most common conditions among adults worldwide. It also presents a challenge among patients undergoing spinal surgery. Use of Teriparatide and bisphosphonates in such patients has been shown to improve… read more here.
Keywords: use; systematic review; fusion; teriparatide ... See more keywords
Weekly teriparatide treatment increases vertebral body strength by improving cortical shell architecture in ovariectomized cynomolgus monkeys.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.01.006
Abstract: Weekly teriparatide treatment is reported to reduce the incidence of osteoporotic vertebral fractures. However, the effect of weekly teriparatide on cortical bone has not been clarified. This study aimed to examine the effects of weekly… read more here.
Keywords: weekly teriparatide; cortical shell; teriparatide; teriparatide treatment ... See more keywords
Synthesis and anti-osteoporosis activity of novel Teriparatide glycosylation derivatives
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra05136e
Abstract: Osteoporosis is a metabolic bone disease that is characterized by low bone mass and micro-architectural deterioration of bones. The mechanism underlying this disease implicates an imbalance between bone resorption and bone remodeling. In 2002, the… read more here.
Keywords: anti osteoporosis; synthesis anti; glycosylation derivatives; teriparatide ... See more keywords
Cost-utility Analysis of Neoadjuvant Teriparatide Therapy in Osteopenic Patients Undergoing Adult Spinal Deformity Surgery
Sign Up to like & getrecommendations! Published in 2022 at "Spine"
DOI: 10.1097/brs.0000000000004409
Abstract: Study Design. A cost-utility analysis study. Objective. This study aims to evaluate the cost-utility of neoadjuvant teriparatide therapy in osteopenic patients undergoing adult spinal deformity (ASD) surgery. Summary of Background Data. There is increasing evidence… read more here.
Keywords: surgery; cost; cost utility; analysis ... See more keywords
SAT0451 COMPARISON OF PHARMACOKINETIC, PHARMACODYNAMIC AND SAFETY OF A TERIPARATIDE BIOSIMILAR AND REFERENCE TERIPARATIDE
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.2009
Abstract: Background: Intas is developing a biosimilar teriparatide. This teriparatide biosimilar has shown similarity to European Union approved teriparatide (EU teriparatide) and United States approved teriparatide (US-teriparatide) in analytical (structural and functional assays) and animal studies1.… read more here.
Keywords: teriparatide teriparatide; biosimilar teriparatide; teriparatide biosimilar; employee ... See more keywords