Statistical crossover and nonextensive behavior of neuronal short-term depression
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biological Physics"
DOI: 10.1007/s10867-017-9474-3
Abstract: The theoretical basis of neuronal coding, associated with short-term degradation in synaptic transmission, is a matter of debate in the literature. In fact, electrophysiological signals are commonly characterized as inversely proportional to stimulus intensity. Among… read more here.
Keywords: term; statistical crossover; term depression; short term ... See more keywords
P292 10Hz rTMS induces long-term depression of GABAergic neurotransmission
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2016.10.400
Abstract: Question The cellular and molecular mechanisms of rTMS-induced neural plasticity remain not well understood. Recent experimental evidence obtained in mouse brain slice cultures disclosed that 10 Hz repetitive magnetic stimulation (rMS) induces long-term potentiation (LTP) of… read more here.
Keywords: long term; rtms; induces long; term depression ... See more keywords
Orexin receptors mediate long-term depression of excitatory synaptic transmission in the spinal cord dorsal horn
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.08.068
Abstract: Neuropeptides orexin-A and -B are related to the regulation of sleep/wakefulness and feeding behaviors. Recently, the peptides have also been shown to yield antinociceptive effects in various pain models. However, it is not clear whether… read more here.
Keywords: term; long term; synaptic transmission; term depression ... See more keywords
Treating Insomnia in Depression: Insomnia Related Factors Predict Long-Term Depression Trajectories
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Consulting and Clinical Psychology"
DOI: 10.1037/ccp0000282
Abstract: Objective: Insomnia and major depressive disorders (MDD) often co-occur, and such comorbidity has been associated with poorer outcomes for both conditions. However, individual differences in depressive symptom trajectories during and after treatment are poorly understood… read more here.
Keywords: depression; insomnia; long term; treatment ... See more keywords
Inhibition of the ISR abrogates mGluR5-dependent long-term depression and spatial memory deficits in a rat model of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Translational Psychiatry"
DOI: 10.1038/s41398-022-01862-9
Abstract: Soluble amyloid-β-protein (Aβ) oligomers, a major hallmark of AD, trigger the integrated stress response (ISR) via multiple pathologies including neuronal hyperactivation, microvascular hypoxia, and neuroinflammation. Increasing eIF2α phosphorylation, the core event of ISR, facilitates metabotropic… read more here.
Keywords: dependent long; term depression; memory deficits; rat model ... See more keywords
Long-term depression–inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2210645119
Abstract: Significance Thyroid hormone (TH) signaling is important for gene regulation and plays an essential role in brain development. However, it remains unknown how TH signaling affects neuronal functions in adulthood. Using a transgenic mouse (Mf-1)… read more here.
Keywords: long term; term depression; thyroid hormone; purkinje cells ... See more keywords
Astrocyte-mediated spike-timing-dependent long-term depression modulates synaptic properties in the developing cortex
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008360
Abstract: Astrocytes have been shown to modulate synaptic transmission and plasticity in specific cortical synapses, but our understanding of the underlying molecular and cellular mechanisms remains limited. Here we present a new biophysicochemical model of a… read more here.
Keywords: spike timing; long term; dependent long; astrocyte mediated ... See more keywords
Alteration of the gut microbiome and correlated metabolism in a rat model of long-term depression
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1116277
Abstract: Objective This study aims to investigate the composition and function of the gut microbiome in long-term depression using an 8-week chronic unpredictable mild stress (CUMS) rat model. Materials and methods Animals were sacrificed after either… read more here.
Keywords: long term; term depression; depression; rat model ... See more keywords
Inhibition of the Interaction Between Group I Metabotropic Glutamate Receptors and PDZ-Domain Proteins Prevents Hippocampal Long-Term Depression, but Not Long-Term Potentiation
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2019.00013
Abstract: The group I metabotropic glutamate (mGlu) receptor subtypes, mGlu1 and mGlu5, strongly regulate hippocampal synaptic plasticity. Both harbor PSD-95/discs-large/ZO-1 (PDZ) motifs at their extreme carboxyl terminals, which allow interaction with the PDZ domain of Tamalin,… read more here.
Keywords: term; long term; group; term depression ... See more keywords
Long Term Depression in Rat Hippocampus and the Effect of Ethanol during Fetal Life
Sign Up to like & getrecommendations! Published in 2017 at "Brain Sciences"
DOI: 10.3390/brainsci7120157
Abstract: Alcohol (ethanol) disturbs cognitive functions including learning and memory in humans, non-human primates, and laboratory animals such as rodents. As studied in animals, cellular mechanisms for learning and memory include bidirectional synaptic plasticity, long-term potentiation… read more here.
Keywords: long term; term depression; ethanol; learning memory ... See more keywords