Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptations.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12766
Abstract: BACKGROUND Fasting is attracting an increasing interest as a potential strategy for managing diseases, including metabolic disorders and complementary cancer therapy. Despite concerns of clinicians regarding protein catabolism and muscle loss, evidence-based clinical data in… read more here.
Keywords: muscle; long term; fasting healthy; term fasting ... See more keywords
Short‐term fasting promotes insulin expression in rat hypothalamus
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.13607
Abstract: In the hypothalamus, insulin takes on many roles involved in energy homoeostasis. Therefore, the aim of this study was to examine hypothalamic insulin expression during the initial phase of the metabolic response to fasting. Hypothalamic… read more here.
Keywords: insulin; hypothalamus; term fasting; expression ... See more keywords
Long-term fasting: Multi-system adaptations in humans (GENESIS) study–A single-arm interventional trial
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.951000
Abstract: Fasting provokes fundamental changes in the activation of metabolic and signaling pathways leading to longer and healthier lifespans in animal models. Although the involvement of different metabolites in fueling human fasting metabolism is well known,… read more here.
Keywords: long term; term fasting; single arm; trial ... See more keywords
Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00161
Abstract: The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fatty-acid regulation, and detoxify ammonia—is susceptible to injuries induced by drugs and toxic substances. Although plasma metabolite profiles are increasingly investigated for… read more here.
Keywords: metabolism; metabolite changes; liver; plasma metabolite ... See more keywords
Short-Term Fasting Synergizes with Solid Cancer Therapy by Boosting Antitumor Immunity
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DOI: 10.3390/cancers14061390
Abstract: Simple Summary Stimulating our body’s own immune response to fight cancer is important for the success of cancer treatment in general. To further improve current cancer therapy, preclinical research shows that short-term fasting diets enhance… read more here.
Keywords: cancer therapy; term fasting; cancer; short term ... See more keywords