Long‐term safety and efficacy of left atrial appendage closure in patients with small appendage orifices measured with transesophageal echocardiography
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23950
Abstract: The Watchman device is the most widely used occluder but is indicated in atrial fibrillation (AF) patients with a maximal left atrial appendage (LAA) orifice diameter between 17 and 31 mm. We aimed to compare the… read more here.
Keywords: long term; term safety; safety efficacy; atrial appendage ... See more keywords
Long‐term safety of a structured transition protocol from parenteral prostanoids to selexipag in pulmonary arterial hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12058
Abstract: Abstract There was no structured method for safely transition from parenteral prostanoids to oral medication. We enrolled 37 idiopathic/hereditary pulmonary arterial hypertension patients receiving triple combination therapy including parenteral prostanoids into structured transition program to… read more here.
Keywords: long term; arterial hypertension; term safety; pulmonary arterial ... See more keywords
Long-term safety and efficacy of opicapone in Japanese Parkinson’s patients with motor fluctuations
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-021-02315-1
Abstract: The double-blind part of the COMFORT-PD (COMt-inhibitor Findings from Opicapone Repeated Treatment for Parkinson’s Disease) study in Japanese levodopa-treated patients with Parkinson’s disease and motor fluctuations found that both opicapone 25 and 50 mg were… read more here.
Keywords: long term; safety; time; motor fluctuations ... See more keywords
Long-Term Safety of Adalimumab in 29,967 Adult Patients From Global Clinical Trials Across Multiple Indications: An Updated Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Therapy"
DOI: 10.1007/s12325-019-01145-8
Abstract: Introduction The safety profile of adalimumab was previously reported in 23,458 patients across multiple indications. Here we report the long-term safety of adalimumab in adults with plaque psoriasis (Ps), hidradenitis suppurativa (HS), rheumatoid arthritis (RA),… read more here.
Keywords: multiple indications; across multiple; long term; safety ... See more keywords
Long-Term Safety and Effectiveness of Adalimumab for Moderate to Severe Psoriasis: Results from 7-Year Interim Analysis of the ESPRIT Registry
Sign Up to like & getrecommendations! Published in 2017 at "Dermatology and Therapy"
DOI: 10.1007/s13555-017-0198-x
Abstract: IntroductionESPRIT (NCT00799877) is an ongoing 10-year international prospective observational registry evaluating the long-term safety and effectiveness of originator adalimumab in routine clinical practice for adult patients with chronic plaque psoriasis. Herein, we report the long-term… read more here.
Keywords: long term; safety; safety effectiveness; term safety ... See more keywords
Long-term safety and efficacy of alirocumab in patients with heterozygous familial hypercholesterolemia: An open-label extension of the ODYSSEY program.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.08.036
Abstract: BACKGROUND AND AIMS ODYSSEY OLE (open-label extension; NCT01954394) included patients diagnosed with heterozygous familial hypercholesterolemia (HeFH), receiving maximally tolerated statins, who had completed one of four Phase 3 double-blind parent studies (all 18 months' duration),… read more here.
Keywords: week; term; long term; parent ... See more keywords
Analysis of the COMPARE-AMI trial: First report of long-term safety of CD133+ cells.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2020.06.004
Abstract: BACKGROUND Data related to long-term safety of intracoronary (IC) injection of CD133+ bone marrow stem cells (BMSC) following an acute myocardial infarction (MI) are still lacking. METHODS COMPARE-AMI is a double-blind, placebo-controlled phase II clinical… read more here.
Keywords: cd133; term safety; trial; long term ... See more keywords
LONG-TERM SAFETY OF TICAGRELOR MONOTHERAPY IN PATIENTS UNDERGOING PCI FOR STABLE CORONARY ARTERY DISEASE IN THE GLOBAL LEADERS STUDY: IMPACT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)30804-6
Abstract: Data on long-term safety and efficacy of ticagrelor in patients with stable coronary artery disease (CAD) and chronic obstructive pulmonary disease (COPD) undergoing percutaneous coronary intervention (PCI) are limited. This is a post-hoc analysis of… read more here.
Keywords: term safety; ticagrelor; stable coronary; long term ... See more keywords
Long-term safety and efficacy of CART-20 cells in patients with refractory or relapsed B-cell non-Hodgkin lymphoma: 5-years follow-up results of the phase I and IIa trials
Sign Up to like & getrecommendations! Published in 2017 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/sigtrans.2017.54
Abstract: Long-term safety and efficacy of CART-20 cells in patients with refractory or relapsed B-cell non-Hodgkin lymphoma: 5-years follow-up results of the phase I and IIa trials read more here.
Keywords: cart cells; long term; safety efficacy; efficacy cart ... See more keywords
Long-term safety of ketamine and esketamine in treatment of depression
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2022.2066651
Abstract: ABSTRACT Introduction Ketamine can produce rapid-acting antidepressant effects. Esketamine (Spravato), the S-enantiomer of racemic ketamine, was approved by the FDA for treatment-resistant depression in 2019. Here we review what is known about the long-term safety… read more here.
Keywords: long term; safety; term safety; ketamine esketamine ... See more keywords
Long-term safety and efficacy of combined percutaneous LAA and PFO/ASD closure: a single-center experience (LAAC combined PFO/ASD closure)
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Medical Devices"
DOI: 10.1080/17434440.2019.1604216
Abstract: ABSTRACT Objectives: To report long-term safety and efficacy of combined percutaneous LAA and PFO/ASD closure. Methods: A retrospective study of 370 consecutive patients undergoing LAAC procedures using the Watchman (WM) device. Data were compared between… read more here.
Keywords: long term; asd closure; pfo asd; group ... See more keywords