The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
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DOI: 10.1073/pnas.2109329119
Abstract: Significance Talin is a mechanosensitive adaptor protein that links integrins to the actin cytoskeleton at cell–extracellular matrix adhesions. Although the C-terminal actin-binding domain ABS3 of talin is required for function, it binds weakly to actin… read more here.
Keywords: actin; terminal actin; binding domain; actin binding ... See more keywords