Copper catalysed cross-dehydrogenative coupling (CDC) reaction of 4-thiazolidinone with terminal alkyne
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.10.068
Abstract: Abstract Cross dehydrogenative coupling (CDC) strategy has been employed for C-alkynylation of 4-thiazolidinone with terminal alkyne under copper catalysis. Present reaction involves coupling of C(sp 3 ) adjacent to sulfur of 4-thiazolidinone with C(sp) of… read more here.
Keywords: dehydrogenative coupling; thiazolidinone terminal; cross dehydrogenative; terminal alkyne ... See more keywords
“Iron catalyzed alkynylation of thiohydantoins with terminal alkyne via cross-dehydrogenative coupling (CDC)”
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153148
Abstract: Abstract Herein, A novel strategy for Iron(II)-catalyzed alkynylation of thiohydantoins with terminal alkyne has been firstly reported. Optimization study was carried out through various catalysts, oxidants and solvents. The merit of this strategy is illustrated… read more here.
Keywords: iron catalyzed; alkynylation thiohydantoins; terminal alkyne; catalyzed alkynylation ... See more keywords
Clicking into Place: Interfacing Terminal Alkyne Biosynthesis with Polyketide Synthases.
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DOI: 10.1016/j.tibtech.2020.04.001
Abstract: Engineering polyketide biosynthesis to enable the production of diverse chemical structures is a major challenge at present. Utilising an established biosynthetic cassette for terminal alkyne production, Porterfield et al. applied docking domain and site-directed mutagenesis… read more here.
Keywords: clicking place; polyketide; biosynthesis; place interfacing ... See more keywords
Palladium-Catalyzed Sonogashira Coupling of a Heterocyclic Phosphonium Salt with a Terminal Alkyne.
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DOI: 10.1021/acs.orglett.2c01800
Abstract: An efficient Sonogashira coupling of a heterocyclic phosphonium salt with a terminal alkyne via C-P bond cleavage was developed. The reactions proceeded smoothly in the presence of palladium catalyst, copper(I) iodide, and N,N-diisopropylethylamine (DIPEA) in… read more here.
Keywords: coupling heterocyclic; phosphonium salt; heterocyclic phosphonium; sonogashira coupling ... See more keywords