Therapeutic and biotechnological applications of substrate specific microbial aminopeptidases
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DOI: 10.1007/s00253-020-10641-9
Abstract: Aminopeptidases (EC 3.4.11.) belongs to exoprotease family, which can catalyze the cleavage of peptide bond which connects the N-terminal amino acid to the penultimate residue in a protein. Aminopeptidases catalyze the process of removal of… read more here.
Keywords: amino; amino acid; biotechnological applications; terminal amino ... See more keywords
Leveraging nature’s biomolecular designs in next-generation protein sequencing reagent development
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DOI: 10.1007/s00253-020-10745-2
Abstract: Next-generation approaches for protein sequencing are now emerging that could have the potential to revolutionize the field in proteomics. One such sequencing method involves fluorescence-based imaging of immobilized peptides in which the N-terminal amino acid… read more here.
Keywords: reagent; amino; amino acid; affinity ... See more keywords
DNA-Unwinding Dynamics of Escherichia coli UvrD Lacking the C-terminal 40 Amino Acids.
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DOI: 10.1016/j.bpj.2020.02.014
Abstract: The E. coli UvrD protein is a nonhexameric DNA helicase that belongs to superfamily I and plays a crucial role in both nucleotide excision repair and methyl-directed mismatch repair. Previous data suggested that wild-type UvrD has… read more here.
Keywords: amino acids; dna; 40c molecules; terminal amino ... See more keywords
Roles of the C-Terminal Amino Acids of Non-Hexameric Helicases: Insights from Escherichia coli UvrD
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DOI: 10.3390/ijms22031018
Abstract: Helicases are nucleic acid-unwinding enzymes that are involved in the maintenance of genome integrity. Several parts of the amino acid sequences of helicases are very similar, and these quite well-conserved amino acid sequences are termed… read more here.
Keywords: amino; amino acids; escherichia coli; terminal amino ... See more keywords