Ankyrin repeat-containing N-Ank proteins shape cellular membranes
Sign Up to like & getrecommendations! Published in 2019 at "Nature Cell Biology"
DOI: 10.1038/s41556-019-0381-7
Abstract: Cells of multicellular organisms need to adopt specific morphologies. However, the molecular mechanisms bringing about membrane topology changes are far from understood—mainly because knowledge of membrane-shaping proteins that can promote local membrane curvatures is still… read more here.
Keywords: amphipathic helix; ank proteins; terminal amphipathic; membrane ... See more keywords
Dissecting the mechanism of action of actinoporins. Role of the N-terminal amphipathic α-helix in membrane binding and pore activity of sticholysins I and II
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202981
Abstract: Actinoporins sticholysin I and sticholysin II (St I, St II) are proposed to lyse model and biomembranes via toroidal pore formation by their N-terminal domain. Based on the hypothesis that peptide fragments can reproduce the… read more here.
Keywords: mechanism action; terminal amphipathic; pore; amphipathic helix ... See more keywords