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Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200124
Abstract: Pyrrole‐imidazole polyamides (PIPs) bind to double‐stranded DNA (dsDNA) with varied sequence selectivity. We synthesized linear PIPs that can bind to narrow minor grooves of polypurine/polypyrimidine sequences and target long recognition sequences but have lower molecular…
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Keywords:
pyrrole imidazole;
modification linear;
terminal cationic;
cationic modification ... See more keywords