Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast
Sign Up to like & getrecommendations! Published in 2020 at "NPJ Breast Cancer"
DOI: 10.1038/s41523-020-00184-7
Abstract: Terminal duct lobular units (TDLUs) are the predominant anatomical structures where breast cancers originate. Having lesser degrees of age-related TDLU involution, measured as higher TDLUs counts or more epithelial TDLU substructures (acini), is related to… read more here.
Keywords: risk; terminal duct; breast; breast cancer ... See more keywords
Associations of Genetic Ancestry with Terminal Duct Lobular Unit Involution among Healthy Women.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the National Cancer Institute"
DOI: 10.1093/jnci/djac063
Abstract: Reduced age-related terminal duct lobular unit (TDLU) involution has been linked to increased breast cancer risk and triple-negative breast cancer (TNBC). Associations of TDLU involution levels with race and ethnicity remain incompletely explored. Herein, we… read more here.
Keywords: tdlu involution; duct lobular; involution; lobular unit ... See more keywords