Understanding terminal erythropoiesis: An update on chromatin condensation, enucleation, and reticulocyte maturation.
Sign Up to like & getrecommendations! Published in 2020 at "Blood reviews"
DOI: 10.1016/j.blre.2020.100740
Abstract: A characteristic feature of terminal erythropoiesis in mammals is extrusion of the highly condensed nucleus out of the cytoplasm. Other vertebrates, including fish, reptiles, amphibians, and birds, undergo nuclear condensation but do not enucleate. Enucleation… read more here.
Keywords: terminal erythropoiesis; condensation; maturation; enucleation ... See more keywords
Proteome remodeling and organelle clearance in mammalian terminal erythropoiesis
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000707
Abstract: Purpose of review The differentiation from colony forming unit-erythroid (CFU-E) cells to mature enucleated red blood cells is named terminal erythropoiesis in mammals. Apart from enucleation, several unique features during these developmental stages include proteome… read more here.
Keywords: proteome remodeling; organelle clearance; terminal erythropoiesis; remodeling organelle ... See more keywords
Crosstalk between terminal erythropoiesis and granulopoiesis within their common niche: the erythromyeloblastic island
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000767
Abstract: Purpose of review The identity of the erythroblastic island (EBI) macrophage (Mϕ) has been under investigation for decades since it was recognized as the first hematopoietic niche ‘nursing’ terminal erythropoiesis. This review will focus on… read more here.
Keywords: erythropoiesis granulopoiesis; terminal erythropoiesis; niche; erythropoiesis ... See more keywords
Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022015724
Abstract: The erythroblastic island (EBI), composed of a central macrophage surrounded by maturing erythroblasts, is the erythroid precursor niche. Despite numerous studies, its precise composition is still unclear. Using multispectral imaging flow cytometry (IFC), in vitro… read more here.
Keywords: granulopoiesis; terminal erythropoiesis; bone marrow; erythropoiesis ... See more keywords