Organellar Glue: A Molecular Tool to Artificially Control Chloroplast–Chloroplast Interactions
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DOI: 10.1021/acssynbio.2c00367
Abstract: Organelles can physically interact to facilitate various cellular processes such as metabolite exchange. Artificially regulating these interactions represents a promising approach for synthetic biology. Here, we artificially controlled chloroplast–chloroplast interactions in living plant cells with… read more here.
Keywords: chloroplast; terminal fragments; control chloroplast; biology ... See more keywords
C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease
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DOI: 10.1038/s41598-017-02841-7
Abstract: This study assesses whether C-terminal fragments (CTF) of the amyloid precursor protein (APP) are present in cerebrospinal fluid (CSF) and their potential as biomarkers for Alzheimer’s disease (AD). Immunoprecipitation and simultaneous assay by Western blotting… read more here.
Keywords: precursor protein; potential biomarkers; biomarkers alzheimer; amyloid precursor ... See more keywords
Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons
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DOI: 10.15252/embr.202153890
Abstract: Aggregation of the multifunctional RNA‐binding protein TDP‐43 defines large subgroups of amyotrophic lateral sclerosis and frontotemporal dementia and correlates with neurodegeneration in both diseases. In disease, characteristic C‐terminal fragments of ~25 kDa ("TDP‐25") accumulate in cytoplasmic… read more here.
Keywords: like inclusions; terminal fragments; sequester; gel like ... See more keywords
Naturally Occurring N-Terminal Fragments of Bovine Milk Osteopontin Are Transported across Models of the Intestinal Barrier
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DOI: 10.3390/biomedicines11030893
Abstract: Osteopontin (OPN) is a bioactive integrin-binding protein found in high concentrations in milk, where it is present both as a full-length protein and as several N-terminally derived fragments. OPN resists gastric digestion, and via interaction… read more here.
Keywords: models intestinal; terminal fragments; intestinal barrier; barrier ... See more keywords