Gallotannin Improves the Photoaged-Related Proteins by Extracellular Signal-Regulated Kinases/c-Jun N-Terminal Kinases Signaling Pathway in Human Epidermal Keratinocyte Cells.
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DOI: 10.1089/jmf.2017.4096
Abstract: Tannins are a type of polyphenols found in several fruits such as grapes and berries, and nuts such as aronias and acorns. Both hydrolyzable tannins and condensed tannins are referred to as tannins. Among the… read more here.
Keywords: kinases jun; jun terminal; extracellular signal; regulated kinases ... See more keywords
Role of c-Jun N-Terminal Kinases (JNKs) in Epilepsy and Metabolic Cognitive Impairment
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DOI: 10.3390/ijms21010255
Abstract: Previous studies have reported that the regulatory function of the different c-Jun N-terminal kinases isoforms (JNK1, JNK2, and JNK3) play an essential role in neurological disorders, such as epilepsy and metabolic-cognitive alterations. Accordingly, JNKs have… read more here.
Keywords: jun terminal; metabolic cognitive; role; terminal kinases ... See more keywords
Design, Synthesis and Characterization of 2-pyridone Derivatives as C-Jun N-terminal Kinases (JNKs) Signaling Pathway Inhibitors
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DOI: 10.5958/0974-360x.2017.00684.9
Abstract: A new series of 2-pyridone derivatives (A1-A6) were synthesized by various substitution and their structures were confirmed by spectral and elemental analyses. The cytotoxic activities of the newly synthesized compounds were docked against JNKs (2WAJ… read more here.
Keywords: pyridone derivatives; jun terminal; kinases jnks; terminal kinases ... See more keywords