1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose Binds to the N-terminal Metal Binding Region to Inhibit Amyloid β-protein Oligomer and Fibril Formation.
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DOI: 10.1016/j.ijms.2016.09.018
Abstract: The early oligomerization of amyloid β-protein (Aβ) is a crucial step in the etiology of Alzheimer's disease (AD), in which soluble and highly neurotoxic oligomers are produced and accumulated inside neurons. In search of therapeutic… read more here.
Keywords: terminal metal; penta galloyl; metal binding; galloyl glucopyranose ... See more keywords