Articles with "terminal methyltransferase" as a keyword



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Improved Cell-Potent and Selective Peptidomimetic Inhibitors of Protein N-Terminal Methyltransferase 1

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27041381

Abstract: Protein N-terminal methyltransferase 1 (NTMT1) recognizes a unique N-terminal X-P-K/R motif (X represents any amino acid other than D/E) and transfers 1–3 methyl groups to the N-terminal region of its substrates. Guided by the co-crystal… read more here.

Keywords: protein terminal; cell potent; terminal methyltransferase; peptidomimetic inhibitors ... See more keywords