Sign Up to like & get
recommendations!
0
Published in 2019 at "Journal of Chemical Sciences"
DOI: 10.1007/s12039-019-1683-9
Abstract: A simple method for naked-eye detection of free amine groups during solid-phase peptide synthesis is reported. The technique involves base-catalyzed cyclization of 2-(2-oxo-2H-acenaphthylene-1-ylidene)-malononitrile (1) and subsequent oxidative substitution of aryl moiety by free amine group…
read more here.
Keywords:
terminal modification;
solid phase;
peptide synthesis;
phase peptide ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00312
Abstract: A key goal of synthetic biology is to enable designed modification of peptides and proteins, both in vivo and in vitro. N- and C-Terminal modification enzymes are crucial in this regard, but there are a…
read more here.
Keywords:
modification;
agemtpt catalyst;
terminal modification;
substrate ... See more keywords
Sign Up to like & get
recommendations!
2
Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc05915k
Abstract: Polytheonamide B (1) is an exceptionally large peptide that forms a transmembrane ion channel. The potent cytotoxicity of 1 against MCF-7 cancer cells originates from its two ion transport functions. Compound 1 depolarizes the plasma…
read more here.
Keywords:
modification polytheonamide;
mcf cancer;
cancer cells;
terminal modification ... See more keywords