Galectin-3 binds selectively to the terminal, non-reducing end of &bgr;(1→4)-galactans, with overall affinity increasing with chain length
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DOI: 10.1093/glycob/cwy085
Abstract: Galactans are linear polysaccharides of β(1→4)-linked galactose residues. Although they can antagonize galectin function, the nature of their binding to galectins needs to be better defined to develop them as drugs. Here, we investigated interactions… read more here.
Keywords: non reducing; length; reducing end; terminal non ... See more keywords