Identification of the active site residues in ATP‐citrate lyase's carboxy‐terminal portion
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DOI: 10.1002/pro.3708
Abstract: ATP‐citrate lyase (ACLY) catalyzes production of acetyl‐CoA and oxaloacetate from CoA and citrate using ATP. In humans, this cytoplasmic enzyme connects energy metabolism from carbohydrates to the production of lipids. In certain bacteria, ACLY is… read more here.
Keywords: site residues; atp citrate; active site; portion ... See more keywords
Missense mutations in the C-terminal portion of the B4GALNT2-encoded glycosyltransferase underlying the Sd(a−) phenotype
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DOI: 10.1016/j.bbrep.2019.100659
Abstract: Sda is a high-frequency carbohydrate histo-blood group antigen, GalNAcβ1-4(NeuAcα2-3)Galβ, implicated in pathogen invasion, cancer, xenotransplantation and transfusion medicine. Complete lack of this glycan epitope results in the Sd(a−) phenotype observed in 4% of individuals who… read more here.
Keywords: portion b4galnt2; b4galnt2; missense mutations; terminal portion ... See more keywords