The C-Terminal Regions of TRAK Proteins Contain MIRO-Independent Mitochondrial Localization Domains.
Sign Up to like & getrecommendations! Published in 2025 at "Cytoskeleton"
DOI: 10.1002/cm.70061
Abstract: Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO-independent MOM-localizing domain… read more here.
Keywords: miro independent; trak proteins; mom; independent mitochondrial ... See more keywords
Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Biology"
DOI: 10.1016/j.jmb.2018.06.047
Abstract: Heterogeneity in small heat shock proteins (sHsps) spans multiple spatiotemporal regimes—from fast fluctuations of part of the protein, to conformational variability of tertiary structure, plasticity of the interfaces, and polydispersity of the inter-converting, and co-assembling… read more here.
Keywords: hspb2 hspb3; terminal regions; human hspb2; regions confer ... See more keywords
Mapping Interactions of the Intrinsically Disordered C-Terminal Regions of Tetrameric p53 by Segmental Isotope Labeling and NMR.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00528
Abstract: The C-terminal region of the tumor suppressor protein p53 contains three domains, nuclear localization signal (NLS), tetramerization domain (TET), and C-terminal regulatory domain (CTD), which are essential for p53 function. Characterization of the structure and… read more here.
Keywords: full length; ctd; intrinsically disordered; terminal regions ... See more keywords
Terminal regions of a protein are a hotspot for low complexity regions and selection
Sign Up to like & getrecommendations! Published in 2024 at "Open Biology"
DOI: 10.1098/rsob.230439
Abstract: Volatile low complexity regions (LCRs) are a novel source of adaptive variation, functional diversification and evolutionary novelty. An interplay of selection and mutation governs the composition and length of low complexity regions. High %GC and… read more here.
Keywords: complexity regions; positively selected; complexity; terminal regions ... See more keywords
Diversity of HLA-A2-Restricted and Immunodominant Epitope Repertoire of Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Protein: Novel Insights among N-Terminal, Central and C-Terminal Regions
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030545
Abstract: The present study sought to search for the immunodominance related to the N-terminal, Central and C-terminal regions of HTLV-1 Tax using novel, cutting-edge peptide microarray analysis. In addition, in silico predictions were performed to verify… read more here.
Keywords: htlv tax; hla; terminal regions; tax ... See more keywords
Nanoscale Structure Determination of Murray Valley Encephalitis and Powassan Virus Non-Coding RNAs
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12020190
Abstract: Viral infections are responsible for numerous deaths worldwide. Flaviviruses, which contain RNA as their genetic material, are one of the most pathogenic families of viruses. There is an increasing amount of evidence suggesting that their… read more here.
Keywords: murray valley; non coding; terminal regions; valley encephalitis ... See more keywords