Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-γ1 Protein.
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DOI: 10.1021/acs.biochem.7b00023
Abstract: SH2 domains recognize phosphotyrosine (pY)-containing peptide ligands and play key roles in the regulation of receptor tyrosine kinase pathways. Each SH2 domain has individualized specificity, encoded in the amino acids neighboring the pY, for defined… read more here.
Keywords: protein; terminal sh2; amino acids; recognition ... See more keywords