Zinc-mediated enantioselective addition of terminal 3-en-1-ynes to cyclic trifluoromethyl ketimines
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DOI: 10.1016/j.jfluchem.2018.01.008
Abstract: Abstract A facile enantioselective addition of terminal 3-en-1-ynes to cyclic N-acyl trifluoromethyl ketimines is reported. In the presence of Zinc/BINOL complexes, a series of enynylated tertiary carbinamines were readily obtained in 90–97% yield with 70–97%… read more here.
Keywords: enantioselective addition; ynes cyclic; trifluoromethyl ketimines; addition terminal ... See more keywords