Direct reprogramming of terminally differentiated cells into neurons: A novel and promising strategy for Alzheimer's disease treatment
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2019.109820
Abstract: Glial activation is a common pathological process of the central nervous system (CNS) in disorders such as Alzheimer's disease (AD). Several approaches have been used to reduce the number of activated astrocytes and microglia in… read more here.
Keywords: alzheimer disease; cells neurons; direct reprogramming; terminally differentiated ... See more keywords
CD69 imposes tumor-specific CD8+ T-cell fate in tumor-draining lymph nodes.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0406
Abstract: Tumor-specific CD8+ T cells play a pivotal role in anti-tumor immunity and are a key target of immunotherapeutic approaches. Intratumoral CD8+ T cells are heterogeneous; Tcf1+ stem-like CD8+ T cells give rise to their cytotoxic… read more here.
Keywords: tumor specific; terminally differentiated; specific cd8; cd8 cells ... See more keywords
Association among Terminally Differentiated T Cells, Frailty, and Dependency in a Group of Cuban Centenarians
Sign Up to like & getrecommendations! Published in 2022 at "Gerontology"
DOI: 10.1159/000525062
Abstract: Introduction: Centenarians are considered a model of successful aging. Cuba exhibits one of the oldest populations in Latin America with more than two thousand centenarians. Methods: This study aimed to evaluate the immune phenotype of… read more here.
Keywords: terminally differentiated; cuban centenarians; group cuban; frailty dependency ... See more keywords