DPV pUL15 possesses a potential NLS, which is important for the location of the terminase complex and for viral proliferation and genome cleavage
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DOI: 10.1186/s13567-024-01420-9
Abstract: In herpesvirus, the terminase subunit pUL15 is involved in cleavage of the viral genome concatemers in the nucleus. Previous studies have shown that herpes simplex virus 1 (HSV-1) pUL15 can enter the nucleus without other… read more here.
Keywords: nls; terminase; genome; pul15 ... See more keywords
Full-length human cytomegalovirus terminase pUL89 adopts a two-domain structure specific for DNA packaging
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DOI: 10.1371/journal.ppat.1008175
Abstract: A key step in replication of human cytomegalovirus (HCMV) in the host cell is the generation and packaging of unit-length genomes into preformed capsids. The enzymes involved in this process are the terminases. The HCMV… read more here.
Keywords: terminase; dna; specific dna; human cytomegalovirus ... See more keywords