Native Mass Spectrometry for the Study of PROTAC GNE‐987‐Containing Ternary Complexes
Sign Up to like & getrecommendations! Published in 2021 at "Chemmedchem"
DOI: 10.1002/cmdc.202100113
Abstract: PROteolysis TArgeting Chimeras (PROTACs) promote the degradation, rather than inhibition, of a drug target as a mechanism for therapeutic treatment. Bifunctional PROTAC molecules allow simultaneous binding of both the target protein and an E3‐Ubiquitin ligase,… read more here.
Keywords: gne 987; native mass; ternary complexes; mass spectrometry ... See more keywords
Fabrication and characterization of gelatin-EGCG-pectin ternary complex: Formation mechanism, emulsion stability, and structure.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12240
Abstract: BACKGROUND Protein-polyphenol-polysaccharide ternary complex particles have better emulsion interfacial stability compared to protein-polysaccharide binary complexes. However, knowledge is scarce when it comes to the fabrication of protein-polyphenol-polysaccharide ternary complexes as interfacial stabilizers and the interactions… read more here.
Keywords: stability; egcg; pectin; ternary complex ... See more keywords
Ternary Cu(II) complexes: synthesis, structural elucidation, and biological studies (DNA binding, cleavage, antibacterial, cytotoxicity)
Sign Up to like & getrecommendations! Published in 2020 at "Research on Chemical Intermediates"
DOI: 10.1007/s11164-020-04140-9
Abstract: The present work focused on the assembly of 2-((2-(4-chlorophenylamino)phenylimino)methyl)-6-methoxyphenol as primary ligand (VBL) and bidentate nitrogen donors, namely 2,2′-bipyridyl (L1), 1,10-phenanthroline (L2), and ethylenediamine (L3) as secondary ligands with Cu(II) ion. The synthesized compounds were… read more here.
Keywords: ternary complexes; synthesis structural; complexes synthesis; structural elucidation ... See more keywords
Synthesis and characterization of ternary complexes of chromium(III) with l-histidine and various diols
Sign Up to like & getrecommendations! Published in 2017 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2013.09.032
Abstract: Abstract Ternary complexes of Cr(III) with l -histidine monohydrochloride and various diols of the type MAB, MA 2 B and MAB 2 were synthesized and characterized in the present study. The structural properties of complexes… read more here.
Keywords: various diols; ternary complexes; characterization ternary; iii histidine ... See more keywords
Structures, fabrication mechanisms, and emulsifying properties of self-assembled and spray-dried ternary complexes based on lactoferrin, oat β-glucan and curcumin: A comparison study.
Sign Up to like & getrecommendations! Published in 2020 at "Food research international"
DOI: 10.1016/j.foodres.2020.109048
Abstract: Protein-polyphenol-polysaccharide non-covalent ternary complexes possess many unique structural and functional properties. However, rare work is available to fabricate the neutral polysaccharide-based ternary complexes. Herein, the ternary complexes composed of lactoferrin (LF), oat β-glucan (OG), and… read more here.
Keywords: lactoferrin oat; spray; ternary complexes; self assembled ... See more keywords
Preparation and characterization of dry β-cyclodextrin-based ternary complexes of haloperidol and lactic acid for drug delivery
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.04.011
Abstract: Abstract This study was aimed to prepare dry β-cyclodextrin (β-CD)-based ternary complexes of haloperidol (HALO) with lactic acid for drug delivery. The influences of different media (buffers pH 3 and pH 6) and preparation methods… read more here.
Keywords: drug; lactic acid; halo lactic; ternary complexes ... See more keywords
Zinc ternary complexes with gabapentin and neurotransmitters: Synthesis, spectral, thermal and molecular docking studies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.126951
Abstract: Abstract Novel series of Zn2+ binary and ternary complexes with antiepileptic drug (gabapentin) and neurotransmitters (glycine, aspartic acid, glutamic acid, serine, γ-aminobutyric acid and adenosine) were synthesized. All the complexes were non-electrolytes where their purity… read more here.
Keywords: gpn; so4 gpn; ternary complexes; docking studies ... See more keywords
Studies of ternary complexes formed in the biocoordination systems including copper(II) ions, polyamines and l-lysine
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DOI: 10.1016/j.poly.2019.114137
Abstract: Abstract Complexation reactions of Cu(II) in the system with l -lysine as well as biogenic amines – PA (putrescine – Put, spermidine – Spd and spermine – Spm) were investigated. It was found that at… read more here.
Keywords: formed biocoordination; complexes formed; ternary complexes; studies ternary ... See more keywords
Rapid Estimation of Binding Constants for Cucurbit[8]uril Ternary Complexes Using Electrochemistry
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DOI: 10.1021/acs.analchem.0c04887
Abstract: Supramolecular complexes are of fundamental interests in biomedicines and adaptive materials, and thus facile methods to determine their binding affinity show usefulness in the design of novel drugs and materials. Herein, we report a novel… read more here.
Keywords: ternary complexes; cucurbit uril; using electrochemistry; binding constants ... See more keywords
PRosettaC: Rosetta Based Modeling of PROTAC Mediated Ternary Complexes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.0c00589
Abstract: Proteolysis-targeting chimeras (PROTACs), which induce degradation by recruitment of an E3 ligase to a target protein, are gaining much interest as a new pharmacological modality. However, designing PROTACs is challenging. Formation of a ternary complex… read more here.
Keywords: protein; ternary complex; ternary complexes; protac ... See more keywords
Binary and Ternary Complexes of Cucurbit[8]uril with Tryptophan, Phenylalanine, and Tyrosine: A Computational Study
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DOI: 10.1021/acsomega.2c00511
Abstract: Selective binding of amino acids, peptides, and proteins by synthetic molecules and elucidation of the geometry and dynamics of the resulting complexes and their strengths are active areas of contemporary research. In recent work, we… read more here.
Keywords: cucurbit uril; amino acids; ternary complexes; tryptophan phenylalanine ... See more keywords