Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction.
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DOI: 10.1016/j.molcel.2021.07.004
Abstract: Nuclear chromosomes transcribe far more RNA than required to encode protein. Here we investigate whether non-coding RNA broadly contributes to cytological-scale chromosome territory architecture. We develop a procedure that depletes soluble proteins, chromatin, and most… read more here.
Keywords: territory architecture; chromatin compaction; rna; chromosome territory ... See more keywords