Enantioselective Dehydroxyhydrogenation of 3-Indolylmethanols by the Combined Use of Benzothiazoline and Chiral Phosphoric Acid: Construction of a Tertiary Carbon Center.
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DOI: 10.1021/acs.orglett.0c00430
Abstract: The chiral indole is an important structure in organic chemistry. We have developed an enantioselective hydrogen transfer reaction of indolylmethanol, which is characterized by the combined use of benzothiazoline and a newly synthesized chiral phosphoric… read more here.
Keywords: carbon center; chiral phosphoric; phosphoric acid; tertiary carbon ... See more keywords
Copper-Catalyzed Asymmetric Addition of Tertiary Carbon Nucleophiles to 2 H-Azirines: Access to Chiral Aziridines with Vicinal Tetrasubstituted Stereocenters.
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DOI: 10.1021/acs.orglett.8b02274
Abstract: A catalytic asymmetric nucleophilic addition of tertiary carbon nucleophiles to 2 H-azirines was established in the presence of the chiral N,N'-dioxide/CuII complex. Various chiral aziridines with vicinal tetrasubstituted stereocenters were obtained in high yields with… read more here.
Keywords: nucleophiles azirines; carbon nucleophiles; chiral aziridines; tertiary carbon ... See more keywords