RNA Polymerase Ribozyme That Recognizes the Template-Primer Complex through Tertiary Interactions.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemistry"
DOI: 10.1021/acs.biochem.3c00091
Abstract: RNA enzymes (ribozymes) often rely on specific base-pairing interactions to engage RNA substrates, which limits the substrate sequence generality of these enzymes. An RNA polymerase ribozyme that was previously optimized by directed evolution to operate… read more here.
Keywords: polymerase ribozyme; polymerase; template primer; ribozyme ... See more keywords
Different tertiary interactions create the same important 3-D features in a distinct flavivirus xrRNA.
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DOI: 10.1261/rna.077065.120
Abstract: During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by structured RNA elements in the 3' untranslated region (UTR) of the… read more here.
Keywords: interactions create; create important; important features; rna ... See more keywords