Discovery of small molecules that target a tertiary-structured RNA
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2213117119
Abstract: Significance There have been increased efforts recently to “drug” RNA using orally bioavailable, low-molecular-weight compounds. This study combines two of the most powerful tools of modern drug discovery, high-throughput screening and structure-based design, to target… read more here.
Keywords: tertiary structured; small molecules; discovery small; structured rna ... See more keywords