Probing RNA structures and functions by solvent accessibility: an overview from experimental and computational perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac112
Abstract: Characterizing RNA structures and functions have mostly been focused on 2D, secondary and 3D, tertiary structures. Recent advances in experimental and computational techniques for probing or predicting RNA solvent accessibility make this 1D representation of… read more here.
Keywords: tertiary structures; structures functions; experimental computational; accessibility ... See more keywords
Cyclic di-AMP, a second messenger of primary importance: tertiary structures and binding mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic acids research"
DOI: 10.1093/nar/gkaa112
Abstract: Cyclic diadenylate (c-di-AMP) is a widespread second messenger in bacteria and archaea that is involved in the maintenance of osmotic pressure, response to DNA damage, and control of central metabolism, biofilm formation, acid stress resistance,… read more here.
Keywords: primary importance; tertiary structures; second messenger; cyclic amp ... See more keywords
Data Size and Quality Matter: Generating Physically-Realistic Distance Maps of Protein Tertiary Structures
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12070908
Abstract: With the debut of AlphaFold2, we now can get a highly-accurate view of a reasonable equilibrium tertiary structure of a protein molecule. Yet, a single-structure view is insufficient and does not account for the high… read more here.
Keywords: data size; structure; tertiary structures; physically realistic ... See more keywords
Molecular Apomorphies in the Secondary and Tertiary Structures of Length-Variable Regions (LVRs) of 18S rRNA Shed Light on the Systematic Position of the Family Thaumastellidae (Hemiptera: Heteroptera: Pentatomoidea)
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24097758
Abstract: The SSU nrDNA, a small subunit of the nuclear ribosomal DNA (coding 18S rRNA), is one of the most frequently sequenced genes in molecular studies in Hexapoda. In insects, including true bugs (Hemiptera: Heteroptera), only… read more here.
Keywords: secondary tertiary; family; tertiary structures; length variable ... See more keywords
Generative Adversarial Learning of Protein Tertiary Structures
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26051209
Abstract: Protein molecules are inherently dynamic and modulate their interactions with different molecular partners by accessing different tertiary structures under physiological conditions. Elucidating such structures remains challenging. Current momentum in deep learning and the powerful performance… read more here.
Keywords: generative adversarial; tertiary structures; protein tertiary; adversarial learning ... See more keywords