TERTp mutations and p53 expression in head and neck cutaneous basal cell carcinomas with different aggressive features
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DOI: 10.1038/s41598-021-89906-w
Abstract: Cutaneous basal cell carcinoma (cBCC) is an economic burden to health services, due to its great morbidity and increasing incidence in old people. Infiltrative cBCCs and cBCCs with micronodular pattern are considered as more aggressive.… read more here.
Keywords: cbccs; tertp mutation; expression; p53 expression ... See more keywords
Association between rs2853669 in TERT gene and the risk and prognosis of human cancer: a systematic review and meta-analysis.
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DOI: 10.18632/oncotarget.15140
Abstract: The polymorphism rs2853669 within the promoter of telomerase reverse transcriptase gene (TERTp) has been debated about its role in cancer risk and prognosis. Additionally, several studies report inconsistent results concerning the modifying effect of rs2853669… read more here.
Keywords: cancer; risk prognosis; rs2853669; tertp mutations ... See more keywords
Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas
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DOI: 10.18632/oncotarget.22650
Abstract: Background Recent studies have reported mutations in the telomerase reverse transcriptase promoter (TERTp) in meningiomas. We sought to determine the frequency, clonality and clinical significance of telomere gene alterations in a cohort of patients with… read more here.
Keywords: grade meningiomas; higher grade; grade; progressive higher ... See more keywords