Abstract 3078: Tesetaxel, a novel, oral taxane, crosses intact blood-brain barrier (BBB) at therapeutically relevant concentrations
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DOI: 10.1158/1538-7445.sabcs18-3078
Abstract: Background: Central nervous system (CNS) metastases in cancers such as breast and lung cancer are common and associated with poor outcomes. The taxanes paclitaxel (P) and docetaxel (D) do not significantly cross the BBB (brain… read more here.
Keywords: taxane; cancer; tesetaxel novel; therapeutically relevant ... See more keywords