Case Report: Canine Strain– and Study Condition–Dependent Formation of Renaut Bodies in Sciatic Nerves of Beagle Dogs
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DOI: 10.1177/0192623319850824
Abstract: Two beagle dog strains were used in a 14-day intrathecal infusion study for a small molecule test article. A moderate number of Renaut bodies (RBs) were observed in the sciatic nerves of control and test… read more here.
Keywords: study; renaut bodies; case report; sciatic nerves ... See more keywords
“Not Everything That Shakes Is a Seizure”: Making the Determination of Test Article–Induced Convulsions in Toxicology Studies
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DOI: 10.1177/1091581818796444
Abstract: Spontaneous unexpected events occasionally develop during the course of rodent preclinical toxicology studies. The presentation of serious adverse events on animal studies may require notification of these events to the Food and Drug Administration if… read more here.
Keywords: everything shakes; test article; toxicology; toxicology studies ... See more keywords