A Randomized, Single‐dose, Phase I Clinical Comparison of a Trastuzumab Biosimilar With a Reference Trastuzumab Formulation in Healthy Chinese Male Volunteers
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DOI: 10.1002/cpdd.1189
Abstract: The test drug, a recombinant humanized monoclonal antibody, is a biosimilar candidate for the reference drug. The purpose of this study was to evaluate the bioequivalence of these two drugs. The study was divided into… read more here.
Keywords: reference; trial; concentration; test drug ... See more keywords
Nephroprotectivity of Coccinia indica leaves against gentamycin-induced nephrotoxicity using in vitro and in vivo models
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Pharmaceutical Science"
DOI: 10.7324/japs.2021.110616
Abstract: The present study intends to explore the efficacy of ethanolic extract of Coccinia indica (EECI) leaves against nephrotoxicity induced by gentamycin (GT) via in vitro and in vivo experiments. Four groups with six Wistar rats… read more here.
Keywords: nephrotoxicity; test drug; vitro vivo; coccinia indica ... See more keywords