Somatic-Immune Cells Crosstalk In-The-Making of Testicular Immune Privilege
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DOI: 10.1007/s43032-021-00721-0
Abstract: Immunological infertility contributes significantly to the etiology of idiopathic male infertility. Shielding the spermatogenic cells from systemic immune responses is fundamental to secure normal production of spermatozoa. The body’s immune system is tuned with the… read more here.
Keywords: immune cells; immune privilege; testicular immune; somatic immune ... See more keywords
Surfactant protein D regulates murine testicular immune milieu and sperm functions
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DOI: 10.1111/aji.12629
Abstract: Surfactant protein D (SP‐D), a pattern recognition protein that regulates inflammation and immune homoeostasis, is expressed by testicular germ cells under the influence of testosterone. This study investigates the role of SP‐D in testicular immune… read more here.
Keywords: protein; surfactant protein; protein regulates; sperm functions ... See more keywords
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility
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DOI: 10.24272/j.issn.2095-8137.2022.440
Abstract: Bacterial or viral infections, such as Brucella, mumps virus, herpes simplex virus, and Zika virus, destroy immune homeostasis of the testes, leading to spermatogenesis disorder and infertility. Of note, recent research shows that SARS-CoV-2 can… read more here.
Keywords: male; testicular immune; immune homeostasis; factor ... See more keywords