Hypomethylation of LINE-1 retrotransposons is associated with cadmium-induced testicular injury
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-10115-5
Abstract: Retrotransposons, as vital regulator of male fertility, are essential for spermatogenesis. Cadmium (Cd) is an environmental toxicant and endocrine disruptor, targeting the reproductive system. Growing evidence shows that Cd exposure can induce male infertility in… read more here.
Keywords: hypomethylation line; cadmium; induced testicular; testicular injury ... See more keywords
Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.113911
Abstract: Di-(2-ethylhexyl) phthalate (DEHP) is a common environmental endocrine disrupting chemical that may induce male reproductive disorders. Exposure to DEHP at a prepubertal stage could lead to prepubertal testicular injury, but the underlying mechanisms remain unclear.… read more here.
Keywords: prepubertal testicular; m6a modification; testicular injury; ethylhexyl phthalate ... See more keywords
Lycium barbarum polysaccharide alleviates nonylphenol exposure induced testicular injury in juvenile zebrafish.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.06.035
Abstract: Nonylphenol is an endocrine disrupting chemicals that can disrupt the organisms' reproductive system, and exists widely in rivers and lakes. Lycium barbarum polysaccharide (LBP) is the main active constituent (about 10%) in Lycium barbarum, which… read more here.
Keywords: barbarum polysaccharide; lycium barbarum; nonylphenol exposure; testicular injury ... See more keywords
Lycopene abrogates di‐(2‐ethylhexyl) phthalate induced testicular injury by modulating oxidative, endocrine and inflammatory changes in mice
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.06.009
Abstract: ABSTRACT Di (2‐ethylhexyl) phthalate (DEHP) is one of the environmental pollutants that causes testicular damage. Lycopene (LYCO), the main active carotenoid in red fruits and vegetables, has well‐known antiinflammatory and antioxidant activities. The present study… read more here.
Keywords: inflammatory; ethylhexyl phthalate; induced testicular; testicular injury ... See more keywords
Curcumin improves the protective effects of quercetin against atrazine‐induced testicular injury in adult Wistar rats
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14445
Abstract: This study evaluated the beneficial protective effect of cotreatment of curcumin (CUR) and quercetin (QUE) on atrazine (ATZ)‐induced testicular toxicity in rats. ATZ challenge diminished luteinizing hormone, follicular stimulating hormone, testosterone and myeloperoxidase enzyme activity,… read more here.
Keywords: protective effects; que; testicular injury; induced testicular ... See more keywords
Arthrospira platensis nanoparticles defeat against diabetes‐induced testicular injury in rat targeting, oxidative, apoptotic, and steroidogenesis pathways
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14456
Abstract: Varieties of studies have been used to investigate the health benefits of Spirulina (Arthrospira platensis); however, more research is needed to examine if its nano form may be utilized to treat or prevent several chronic… read more here.
Keywords: diabetic rats; testicular injury; steroidogenesis; arthrospira platensis ... See more keywords
GnRH Antagonist Improves Pubertal Cyclophosphamide-Induced Long-Term Testicular Injury in Adult Rats
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Endocrinology"
DOI: 10.1155/2018/4272575
Abstract: Background Gonadal injury following chemotherapy is of increasing importance with the continuous improvement of survival rates. The protection of gonadotropin hormone antagonist (GnRHant) in long-term adult survivors of adolescent cancers and some autoimmune diseases has… read more here.
Keywords: term testicular; cpa; long term; testicular injury ... See more keywords
Effect of Flavonoid-Rich Extract From Dalbergiella welwitschii Leaf on Redox, Cholinergic, Monoaminergic, and Purinergic Dysfunction in Oxidative Testicular Injury: Ex Vivo and In Silico Studies
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics and Biology Insights"
DOI: 10.1177/11779322221115546
Abstract: The antioxidant, cholinergic, monoaminergic, and purinergic activities of flavonoid-rich extract from Dalbergiella welwitschii leaf (FEDW) were investigated on oxidative testicular injury (ex vivo) due to the local report on the use of this plant as… read more here.
Keywords: extract; testicular injury; cholinergic monoaminergic; oxidative testicular ... See more keywords
Nutraceuticals: A New Challenge against Cadmium-Induced Testicular Injury
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14030663
Abstract: Cadmium (Cd) is a widespread heavy metal and a ubiquitous environmental toxicant. For the general population, the principal causes of Cd exposure are cigarette smoking, air pollution and contaminated water and food consumption, whereas occupational… read more here.
Keywords: testicular injury; induced testicular; cadmium; nutraceuticals new ... See more keywords
Difenoconazole Exposure Induces Retinoic Acid Signaling Dysregulation and Testicular Injury in Mice Testes
Sign Up to like & getrecommendations! Published in 2023 at "Toxics"
DOI: 10.3390/toxics11040328
Abstract: Difenoconazole (DFZ) is a broad-spectrum triazole fungicide that is widely utilized in agriculture. Although DFZ has been demonstrated to induce reproductive toxicity in aquatic species, its toxic effects on the mammalian reproductive system have yet… read more here.
Keywords: testicular injury; injury mice; retinoic acid; mice ... See more keywords