A testis-derived macroporous 3D scaffold as a platform for the generation of mouse testicular organoids.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c8bm01001c
Abstract: Extracellular matrix-derived scaffolds provide an efficient platform for the generation of organ-like structures. Successful development of testicular organoids (TOs) with the capability of supporting complete spermatogenesis has not been reported yet. Here, we have developed… read more here.
Keywords: testis derived; platform generation; tdss; generation ... See more keywords
Testicular organoids: a new model to study the testicular microenvironment in vitro?
Sign Up to like & getrecommendations! Published in 2017 at "Human Reproduction Update"
DOI: 10.1093/humupd/dmx036
Abstract: BACKGROUND In recent decades, a broad range of strategies have been applied to model the testicular microenvironment in vitro. These models have been utilized to study testicular physiology and development. However, a system that allows… read more here.
Keywords: medicine; testicular organoids; physiology; vitro ... See more keywords
Regulation of cell types within testicular organoids.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrinology"
DOI: 10.1210/endocr/bqab033
Abstract: Organoids are three-dimensional structures grown in vitro that emulate the cytoarchitecture and functions of true organs. Therefore, testicular organoids arise as an important model for research on male reproductive biology. These organoids can be generated… read more here.
Keywords: research; testicular organoids; cell types; biology ... See more keywords
Organotypic Rat Testicular Organoids for the Study of Testicular Maturation and Toxicology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.892342
Abstract: An in vitro system to study testicular maturation in rats, an important model organism for reproductive toxicity, could serve as a platform for high-throughput drug and toxicity screening in a tissue specific context. In vitro… read more here.
Keywords: testicular organoids; toxicology; maturation; rat testicular ... See more keywords