Articles with "testicular toxicity" as a keyword



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Revisiting the testicular toxicity of cyanide: Assessment of the new and existing literature

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Published in 2023 at "Birth Defects Research"

DOI: 10.1002/bdr2.2160

Abstract: Based on new testing, we re‐assess U.S. EPA and California OEHHA conclusions regarding male reproductive toxicity associated with cyanide exposure. read more here.

Keywords: assessment new; cyanide assessment; testicular toxicity; toxicity cyanide ... See more keywords
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Di‐(2‐ethylhexyl) phthalate (DEHP)‐induced testicular toxicity through Nrf2‐mediated Notch1 signaling pathway in Sprague–Dawley rats

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Published in 2018 at "Environmental Toxicology"

DOI: 10.1002/tox.22559

Abstract: Di‐(2‐ethylhexyl) phthalate (DEHP) is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Many studies have shown that DEHP causes testicular toxicity through oxidative stress, but the specific… read more here.

Keywords: dehp induced; testicular toxicity; toxicity; pathway ... See more keywords
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Potential of sperm small non-coding RNAs as biomarkers of testicular toxicity in a doxorubicin-induced mouse model

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Published in 2021 at "Biochemistry and Biophysics Reports"

DOI: 10.1016/j.bbrep.2021.101160

Abstract: Testicular toxicity is a major concern in cancer chemotherapy and drug development as it can result in infertility; however, there are no effective biomarkers for this adverse effect. To identify new biomarkers, we investigated the… read more here.

Keywords: coding rnas; testicular toxicity; small non; non coding ... See more keywords
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Silver nanoparticles testicular toxicity in rat.

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Published in 2019 at "Environmental toxicology and pharmacology"

DOI: 10.1016/j.etap.2019.103194

Abstract: To evaluate the potential testicular toxicity induced by silver nanoparticles (AgNPs) in Sprague Dawley rate. The protocol study was designed as follows: G1: 30 adult male rats were kept as control. G2: 30 adult male… read more here.

Keywords: significant decrease; testicular toxicity; adult male; silver nanoparticles ... See more keywords
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Ethanolic extract of Moringa oleifera leaves alleviate cyclophosphamide-induced testicular toxicity by improving endocrine function and modulating cell specific gene expression in mouse testis.

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Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.112922

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Moringa oleifera Lam. is known for its nutritional and ethno medicinal values due to the presence of wide array of phytochemicals with multiple biological activities. We have previously reported that ethanolic extract of… read more here.

Keywords: spermatogonial cells; moringa oleifera; testicular toxicity; expression ... See more keywords
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Lack of beneficial effect of activated charcoal in lead induced testicular toxicity in male albino rats

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Published in 2017 at "Middle East Fertility Society Journal"

DOI: 10.1016/j.mefs.2017.02.001

Abstract: Abstract Objective: Lead is a multi-organ toxicant implicated in various diseases including testicular toxicity. In search of cheap and readily available antidote this study has investigated a beneficial role of activated charcoal in lead induced… read more here.

Keywords: activated charcoal; testicular toxicity; induced testicular; lead ... See more keywords
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Untargeted LC‐MS‐based metabonomics revealed that aristolochic acid I induces testicular toxicity by inhibiting amino acids metabolism, glucose metabolism, &bgr;‐oxidation of fatty acids and the TCA cycle in male mice

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Published in 2019 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2019.04.014

Abstract: &NA; As the main toxic component of aristolochic acid, aristolochic acid I (AAI) is primarily found in Aristolochiaceae plants such as Aristolochia, Aristolochia fangchi and Caulis aristolochiae manshuriensis. AAI has been proven to be carcinogenic,… read more here.

Keywords: metabolism; fatty acids; testicular toxicity; acid ... See more keywords
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Arrested Acetylene-Induced Pulmonary and Testicular Toxicity in Rats Through Treatment With Polyphenols

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Published in 2022 at "Drug and Chemical Toxicology"

DOI: 10.1080/01480545.2022.2066115

Abstract: Abstract Occupational exposure to potentially harmful substances is one of the dangers associated with industrial jobs. This study evaluated the modulatory influence of selected dietary polyphenols on the pulmonotoxic and testiculotoxic effects of crude acetylene,… read more here.

Keywords: pulmonary testicular; testicular toxicity; induced pulmonary; arrested acetylene ... See more keywords
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High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial Cells

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Published in 2017 at "Toxicological Sciences"

DOI: 10.1093/toxsci/kfw178

Abstract: Bisphenol A (BPA), an endocrine-disrupting compound, was found to be a testicular toxicant in animal models. Bisphenol S (BPS), bisphenol AF (BPAF), and tetrabromobisphenol A (TBBPA) were recently introduced to the market as alternatives to… read more here.

Keywords: spermatogonial cells; bisphenol; content analysis; testicular toxicity ... See more keywords
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Evaluation of ameliorating effect of lycopene against testicular toxicity due to diethylnitrosamine using biochemical, spermatological and histopathological data

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Published in 2019 at "Andrologia"

DOI: 10.1111/and.13274

Abstract: The aim of this study was to evaluate the possible therapeutic or protective effects of lycopene on diethylnitrosamine (DEN)‐induced testicular lipid peroxidation and on the associated changes in spermatological parameters and histopathological architecture of rat… read more here.

Keywords: biochemical spermatological; effect lycopene; lycopene den; den lycopene ... See more keywords
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Investigation of the effect of hesperidin on some reproductive parameters in testicular toxicity induced by Bisphenol A

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Published in 2022 at "Andrologia"

DOI: 10.1111/and.14562

Abstract: Bisphenol A (BPA) is one of the chemicals that cause dysfunction and infertility in testicles. Therefore, it is crucial to develop effective treatments against this damage. In this study, the effects of Hesperidin (HESP), a… read more here.

Keywords: inflammation; testicular toxicity; damage; toxicity induced ... See more keywords