Should embryos with autosomal monosomy by preimplantation genetic testing for aneuploidy be transferred?: Implications for embryo selection from a systematic literature review of autosomal monosomy survivors
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DOI: 10.1002/pd.5185
Abstract: To review the literature for survival and phenotypes of liveborns with autosomal monosomy to inform decisions regarding transfer of in vitro fertilization‐derived embryos reported as monosomic on preimplantation genetic testing for aneuploidy (PGT‐A). read more here.
Keywords: genetic testing; monosomy; testing aneuploidy; preimplantation genetic ... See more keywords
Prognostic role of preimplantation genetic testing for aneuploidy in medically indicated fertility preservation.
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DOI: 10.1016/j.fertnstert.2019.09.040
Abstract: OBJECTIVE To investigate the use of preimplantation genetic testing for aneuploidy (PGT-A) among patients pursuing embryo banking (EB) for medically indicated fertility preservation (FP). DESIGN Retrospective cohort. SETTING University-affiliated fertility center. PATIENTS All patients who… read more here.
Keywords: genetic testing; pgt; testing aneuploidy; preimplantation genetic ... See more keywords
Preimplantation Genetic Testing for Aneuploidy: Current Perspectives.
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DOI: 10.1055/s-0041-1731828
Abstract: Despite improvements in assisted reproduction techniques (ARTs), live birth rates remain suboptimal, particularly in women with advanced maternal age (AMA). The leading cause of poor reproductive outcomes demonstrated in women with AMA, as well as… read more here.
Keywords: genetic testing; aneuploidy current; testing aneuploidy; preimplantation genetic ... See more keywords
Preimplantation genetic testing for aneuploidy: are we examining the correct outcomes?
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DOI: 10.1093/humrep/deaa224
Abstract: Questions continue to be raised regarding the benefit of genetic assessment of embryos prior to transfer in IVF, specifically with regards to preimplantation genetic testing for aneuploidy (PGT-A). To evaluate and quantify these concerns, we… read more here.
Keywords: genetic testing; examining correct; testing aneuploidy; preimplantation genetic ... See more keywords
We have reached a dead end for preimplantation genetic testing for aneuploidy.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction"
DOI: 10.1093/humrep/deac052
Abstract: The hypothesis of preimplantation genetic testing for aneuploidy (PGT-A) was first proposed 20 years ago, suggesting that during IVF elimination of aneuploid embryos prior to transfer will improve implantation rates of remaining embryos and, therefore, increase… read more here.
Keywords: embryos; genetic testing; preimplantation genetic; testing aneuploidy ... See more keywords
Preimplantation genetic testing for aneuploidy (PGT‐A): The biology, the technology and the clinical outcomes
Sign Up to like & getrecommendations! Published in 2019 at "Australian and New Zealand Journal of Obstetrics and Gynaecology"
DOI: 10.1111/ajo.12960
Abstract: Preimplantation genetic testing for aneuploidy (PGT‐A) seeks to identify preimplantation embryos with a normal chromosome complement (euploid) during in vitro fertilisation (IVF). By sifting out embryos with abnormal chromosome numbers (aneuploid), PGT‐A should theoretically improve… read more here.
Keywords: genetic testing; pgt; testing aneuploidy; biology ... See more keywords
Comparison of preimplantation genetic testing for aneuploidy versus intracytoplasmic sperm injection in severe male infertility
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DOI: 10.1111/and.14065
Abstract: The retrospective cohort study was conducted to evaluate the effectiveness of preimplantation genetic testing for aneuploidy (PGT‐A) for severe male factor (SMF) infertility on pregnancy outcomes in comparison with intracytoplasmic sperm injection (ICSI). A total… read more here.
Keywords: severe male; genetic testing; intracytoplasmic sperm; testing aneuploidy ... See more keywords
A systematic review exploring the patient decision‐making factors and attitudes towards pre‐implantation genetic testing for aneuploidy and gender selection
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DOI: 10.1111/aogs.13973
Abstract: Pre‐implantation genetic testing for aneuploidy (PGT‐A) is in high demand worldwide, with ongoing debate among medical societies as to which patient groups it should be offered. The psychological aspects for patients regarding its use, lag… read more here.
Keywords: genetic testing; pre implantation; implantation genetic; testing aneuploidy ... See more keywords
Mosaic results after preimplantation genetic testing for aneuploidy may be accompanied by changes in global gene expression
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1180689
Abstract: Aneuploidy in preimplantation embryos is a major cause of human reproductive failure. Unlike uniformly aneuploid embryos, embryos diagnosed as diploid-aneuploid mosaics after preimplantation genetic testing for aneuploidy (PGT-A) can develop into healthy infants. However, the… read more here.
Keywords: preimplantation genetic; testing aneuploidy; genetic testing; gene expression ... See more keywords
In vitro fertilization with single-Nucleotide polymorphism microarray-based preimplantation genetic testing for aneuploidy significantly improves clinical outcomes in infertile women with recurrent pregnancy loss: A randomized controlled trial
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive and Developmental Medicine"
DOI: 10.4103/2096-2924.281852
Abstract: Objective: To evaluate the effect of preimplantation genetic testing for aneuploidy (PGT-A) in infertile patients with recurrent pregnancy loss (RPL). Methods: A prospective randomized clinical trial was performed in a university-affiliated fertility center in Shanghai,… read more here.
Keywords: genetic testing; pregnancy; testing aneuploidy; preimplantation genetic ... See more keywords