TPMT and NUDT15 testing for thiopurine therapy: A major tertiary hospital experience and lessons learned
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DOI: 10.3389/fphar.2022.837164
Abstract: Variants in thiopurine methyltransferase (TPMT) and nudix hydrolase 15 (NUDT15) are associated with an accumulation of cytotoxic metabolites leading to increased risk of drug-related toxicity with standard doses of thiopurine drugs. We established TPMT and… read more here.
Keywords: testing thiopurine; gene; thiopurine therapy; tpmt nudt15 ... See more keywords