Combined RNA/tissue profiling identifies novel Cancer/Testis genes.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.12900
Abstract: Cancer/Testis (CT) genes are induced in germ cells, repressed in somatic cells and de-repressed in somatic tumors, where these genes can contribute to cancer progression. CT gene identification requires data obtained using standardized protocols and… read more here.
Keywords: testis; tissue; testis genes; cancer testis ... See more keywords
A pilot study on the effect of early provision of dietary docosahexaenoic acid on testis development, functions, and sperm quality in rats exposed to prenatal ethanol.
Sign Up to like & getrecommendations! Published in 2019 at "Birth defects research"
DOI: 10.1002/bdr2.1614
Abstract: BACKGROUND Prenatal ethanol (EtOH) exposure is associated with adverse effect on the male reproductive function. Dietary docosahexaenoic acid (DHA) is known to improve testis function and sperm parameters, thereby male fertility. This study piloted whether… read more here.
Keywords: testis; prenatal ethanol; dha; etoh ... See more keywords
Contribution of the coelomic epithelial cells specific to the left testis in the chicken embryo
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24469
Abstract: Background: The left male gonad in the chicken embryo has a thickened cortical layer, but it eventually becomes flattened after the onset of testicular development. Because the destination of the cortical cells migrating from the… read more here.
Keywords: testis; epithelial cells; chicken embryo; left testis ... See more keywords
Food‐grade titanium dioxide (E171) by solid or liquid matrix administration induces inflammation, germ cells sloughing in seminiferous tubules and blood‐testis barrier disruption in mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3842
Abstract: Food‐grade titanium dioxide labeled as E171 has been approved for human consumption by the Food and Drug Administration (USA) and by the European Union for five decades. However, titanium dioxide has been classified as a… read more here.
Keywords: testis; blood testis; titanium dioxide; testis barrier ... See more keywords
Ameliorative effect of ellagic acid and Vitamin C against malathion‐induced toxicity in testis of adult Wistar rats
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23314
Abstract: The pesticide malathion (MT), an organophosphate, is highly neurotoxic and causes cholinergic disorders as well as cytotoxicity, genotoxicity, mutagenicity, carcinogenicity and reproductive toxicity. Our purpose was to study the effect of ellagic acid (EA) and… read more here.
Keywords: induced toxicity; toxicity; testis; acid vitamin ... See more keywords
Regulation by Hsp27/P53 in testis development and sperm apoptosis of male cattle (cattle‐yak and yak)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26822
Abstract: Heat shock protein 27 (Hsp27)/protein 53 (P53) plays an important role in testis development and spermatozoa regulation, but the relationship between Hsp27/P53 and infertility in cattle is unclear. Here, we focus on male cattle‐yak and… read more here.
Keywords: testis; hsp27 p53; expression; cattle yak ... See more keywords
cd44 deletion suppresses atypia in the precancerous mouse testis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22961
Abstract: Loss‐of‐function of RHAMM causes hypofertility and testicular atrophy in young mice, followed by germ cell neoplasia in situ (GCNIS) of the testis, cellular atypia, and development of the testicular germ cell tumor (TGCT) seminoma. These… read more here.
Keywords: gcnis; testis; cd44 deletion; oncogenic progression ... See more keywords
Cry1 deficiency leads to testicular dysfunction and altered expression of genes involved in cell communication, chromatin reorganization, spermatogenesis, and immune response in mouse testis
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22968
Abstract: Cryptochrome (Cry)1 is essential for generating circadian rhythm in central and many peripheral oscillators; however, its role in male reproduction remains unclear. We investigated this question using Cry1 knockout (KO) mice. We found that Cry1… read more here.
Keywords: cry1; testis; cry1 deficiency; expression ... See more keywords
An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23309
Abstract: Sertoli cells (SCs) are presumed to be the center of testis differentiation because they provide both structural support and biological regulation for spermatogenesis. Previous studies suggest that SCs control germ cell (GC) count and Leydig… read more here.
Keywords: testis; ablation; role; cell ... See more keywords
Simple, once‐off mapping of various, recurrent immunostaining patterns of proliferating cell nuclear antigen in spermatogonia at the immature pole of the testis of adult wild‐caught blue shark, Prionace glauca: Correlations with changes in testicular status
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23429
Abstract: This study was a single time‐point mapping of various immunostaining patterns revealed with the proliferating cell nuclear antigen (PCNA) PC10 antibody in spermatogonia at the immature pole of the testis of the Blue shark (Prionace… read more here.
Keywords: testis; immature pole; spermatogonia; immunostaining patterns ... See more keywords
Systematic analysis of the ubiquitome in mouse testis
Sign Up to like & getrecommendations! Published in 2021 at "PROTEOMICS"
DOI: 10.1002/pmic.202100025
Abstract: A growing body of evidence now supports the fact that protein ubiquitination is an important modification during the regulation of spermatogenesis. However, little is known about the ubiquitome of the testis. In this study, we… read more here.
Keywords: testis; mouse testis; systematic analysis; ubiquitome mouse ... See more keywords