Cancer testis antigen expression across T‐cell lymphoma subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Hematological Oncology"
DOI: 10.1002/hon.2785
Abstract: To better understand the expression of cancer testis antigens (CTA) and its association with clinical outcomes on patients with T-cell lymphomas, we sought to establish a baseline level of expression of CTA across a diversity… read more here.
Keywords: cta; expression; testis antigen; cancer testis ... See more keywords
A cancer/testis antigen, NY-SAR-35, induces EpCAM, CD44, and CD133, and activates ERK in HEK293 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.105
Abstract: The cancer/testis (CT) antigen NY-SAR-35 gene is located on the X chromosome and is aberrantly expressed in various cancers but not in normal tissues, other than testes. Previously, we reported the expression of NY-SAR-35 enhanced… read more here.
Keywords: hek293; hek293 cells; cancer testis; sar ... See more keywords
Decitabine increases neoantigen and cancer testis antigen expression to enhance T-cell–mediated toxicity against glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noac107
Abstract: Abstract Background Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults. Despite maximal treatment, median survival remains dismal at 14–24 months. Immunotherapies, such as checkpoint inhibition, have revolutionized management of some… read more here.
Keywords: cell; neoantigen cancer; testis antigen; tumor ... See more keywords
Epitope Analysis of Murine and Chimeric Monoclonal Antibodies Recognizing the Cancer Testis Antigen PRAME
Sign Up to like & getrecommendations! Published in 2020 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672920030072
Abstract: Abstract We investigated the epitope specificity of different monoclonal antibodies recognizing the cancer testis antigen PRAME. Antibody 5D3 binds to the fragment of PRAME corresponding to 160–180 amino acid residues. Antibodies 6H8 and F11 bind… read more here.
Keywords: testis antigen; monoclonal antibodies; cancer testis; antibodies recognizing ... See more keywords
Commentary: Cancer-testis antigen lactate dehydrogenase C4 as a novel biomarker of male infertility and cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1115620
Abstract: COPYRIGHT © 2023 Naik and Decock. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the… read more here.
Keywords: lactate dehydrogenase; antigen lactate; commentary cancer; testis antigen ... See more keywords
Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12030689
Abstract: The SF-1 transcription factor target gene FATE1 encodes a cancer-testis antigen that has an important role in regulating apoptosis and response to chemotherapy in adrenocortical carcinoma (ACC) cells. Autoantibodies directed against FATE1 were previously detected… read more here.
Keywords: adult; response; expression; cancer testis ... See more keywords
Cancer testis antigen subfamilies: Attractive targets for therapeutic vaccine (Review)
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Oncology"
DOI: 10.3892/ijo.2023.5519
Abstract: Cancer-testis antigen (CTA) is a well-accepted optimal target library for cancer diagnosis and treatment. Most CTAs are located on the X chromosome and aggregate into large gene families, such as the melanoma antigen, synovial sarcoma… read more here.
Keywords: cancer; testis antigen; vaccine; antigen ... See more keywords
Serum immunoreactivity of cancer/testis antigen OY-TES-1 and its tissues expression in glioma
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DOI: 10.3892/ol.2017.5799
Abstract: OY-TES-1 is a member of the cancer/testis antigen family that is expressed in healthy testis tissue and certain types of cancerous tissue. The present study aimed to analyze the expression pattern of OY-TES-1 and serum… read more here.
Keywords: testis; glioma; expression; cancer testis ... See more keywords