Targeted photodynamic therapy of cancer using a novel gallium (III) tris (ethoxycarbonyl) corrole conjugated‐mAb directed against cancer/testis antigens 83
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1601
Abstract: Photodynamic therapy (PDT) is a noninvasive, highly selective approach to the treatment of tumors. However, its therapeutic effect is limited by long‐lasting skin phototoxicity. Therefore, to compromise this shortcoming, it is preferable to deliver photosensitizers… read more here.
Keywords: ct83; photodynamic therapy; gallium iii; testis antigens ... See more keywords
Cancer Testis Antigens in Sarcoma: Expression, Function and Immunotherapeutic Application.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.10.024
Abstract: Sarcomas are a group of heterogeneous malignancies of mesenchymal origin. Patient outcomes remain especially grim for those with recurrent or metastatic disease, and current therapeutic strategies have not significantly improved outcomes over the past few… read more here.
Keywords: testis; function; testis antigens; expression ... See more keywords
The role of Cancer/Testis Antigens in Multiple Myeloma pathogenesis and their application in disease monitoring and therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2018.09.010
Abstract: A unique group of genes, encoding tumour associated antigens, known as the Cancer/Testis Antigens (CTAs), have been explored as novel markers of disease progression and as targets of immunotherapy in several cancers, including the haematological… read more here.
Keywords: testis antigens; disease; pathogenesis; multiple myeloma ... See more keywords
Cancer/Testis Antigens into mitochondria: a hub between spermatogenesis, tumorigenesis and mitochondrial physiology adaptation.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.11.002
Abstract: Cancer/Testis Antigens (CTAs) genes are expressed only during spermatogenesis and tumorigenesis. Both processes share common specific metabolic adaptation related to energy supply, with a glucose to lactate gradient, leading to changes in mitochondrial physiology paralleling… read more here.
Keywords: spermatogenesis tumorigenesis; testis antigens; mitochondrial physiology; physiology ... See more keywords
Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2131096
Abstract: ABSTRACT Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths worldwide due to high recurrence rates after curative treatment and being frequently diagnosed at an advanced stage. Immune-checkpoint inhibition (ICPI) has yielded impressive… read more here.
Keywords: cell; hepatocellular carcinoma; testis antigens; hcc patients ... See more keywords
PO-341 The role of cancer/testis antigens from MAGE-A family and NY-ESO-1 in ductal carcinoma in situ (DCIS)
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.853
Abstract: Introduction Cancer/testis antigens (CTA) are a large family of tumor-associated antigens expressed in human tumours of different histological origin, but not in normal tissues except for testis and placenta. Several immunohistochemical studies confirmed the association… read more here.
Keywords: mage; testis antigens; family; cancer testis ... See more keywords
Cancer-testis antigens in ovarian cancer: implication for biomarkers and therapeutic targets
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ovarian Research"
DOI: 10.1186/s13048-018-0475-z
Abstract: Ovarian cancer remains the most fatal gynecologic malignancy worldwide due to delayed diagnosis as well as recurrence and drug resistance. Thus, the development of new tumor-related molecules with high sensitivity and specificity to replace or… read more here.
Keywords: antigens ovarian; testis antigens; ovarian cancer; cancer testis ... See more keywords
Engineering Cancer/Testis Antigens With Reversible S-Cationization to Evaluate Antigen Spreading
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.869393
Abstract: Serum autoantibody to cancer/testis antigens (CTAs) is a critical biomarker that reflects the antitumor immune response. Quantitative and multiplexed anti-CTA detection arrays can assess the immune status in tumors and monitor therapy-induced antitumor immune reactions.… read more here.
Keywords: cancer; testis antigens; cationization; antigen ... See more keywords
Electrostatic Complementarities of Glioblastoma-Resident T-Cell Receptors and Cancer Testis Antigens Linked to Poor Outcomes and High Levels of Sphingosine Kinase-2 Expression
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12040575
Abstract: Simple Summary The chemical complementarity of glioblastoma, tumor-resident T-cell receptors and cancer testis antigens were associated with a worse outcome. Additionally, the high expression of immune marker and low expression of apoptosis genes were associated… read more here.
Keywords: cell; expression; testis antigens; cancer ... See more keywords