Does Patient-Applied Testosterone Replacement Therapy Pose Risk for Blood Pressure Elevation? Circadian Medicine Perspectives.
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DOI: 10.1002/cphy.c220014
Abstract: We reviewed medication package inserts, US Food and Drug Administration (FDA) reports, and journal publications concerning the 10 nonbiosimilar patient-applied (PA) testosterone (T) replacement therapies (TRTs) for intraday serum T patterning and blood pressure (BP)… read more here.
Keywords: blood pressure; patient applied; testosterone replacement; blood ... See more keywords
The appropriateness and persistence of testosterone replacement therapy in Ontario
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DOI: 10.1002/pds.4083
Abstract: To examine the concordance between testosterone replacement therapy (TRT) use and established reimbursement criteria, as well as compare the persistence of use among available formulations (injectable, oral, topical gel, transdermal patch) among elderly men in… read more here.
Keywords: testosterone replacement; replacement therapy; appropriateness persistence;
Oncological safety and functional outcomes of testosterone replacement therapy in symptomatic adult-onset hypogonadal prostate cancer patients following robot-assisted radical prostatectomy
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DOI: 10.1007/s00345-020-03475-7
Abstract: Testosterone replacement therapy (TRT) remains controversial in men with treated prostate cancer. We assessed its safety and functional impacts in patients after definitive surgical treatment with robotic-assisted radical prostatectomy (RARP). We performed a retrospective analysis… read more here.
Keywords: prostate; replacement therapy; prostate cancer; testosterone replacement ... See more keywords
Monitoring testosterone replacement therapy with transdermal gel: when and how?
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DOI: 10.1007/s40618-019-01082-x
Abstract: Testosterone replacement therapy (TRT) is recommended for the treatment of most cases of male hypogonadism. Transdermal testosterone (T) gels are commonly used in clinical practice; however, there is little evidence concerning how to monitor dosage… read more here.
Keywords: treatment; testosterone replacement; replacement therapy; gel ... See more keywords
Testosterone replacement for male military personnel – A potential countermeasure to reduce injury and improve performance under extreme conditions
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DOI: 10.1016/j.ebiom.2019.08.015
Abstract: Tactical operators, inclusive of soldiers in the military, are reliant upon their physiological and psychological state in often volatile and extreme life or death situations that require correct decisions and precise actions to ensure operational… read more here.
Keywords: military personnel; male military; replacement male; testosterone replacement ... See more keywords
Testosterone Replacement Therapy in Hypogonadal Men.
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DOI: 10.1016/j.ecl.2021.11.005
Abstract: All approved testosterone replacement methods, when used according to recommendations, can restore normal serum testosterone concentrations, and relieve symptoms in most hypogonadal men. Selection of the method depends on the patient's preference with advice from… read more here.
Keywords: testosterone replacement; hypogonadal men; replacement therapy; therapy hypogonadal ... See more keywords
Comparison of American Urological Association and Endocrine Society guidelines on testosterone replacement
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DOI: 10.1038/s41443-021-00477-w
Abstract: Low testosterone affects an increasing number of patients each year resulting in a steady increase in prescriptions for testosterone replacement therapy (TRT). In 2018, the American Urological Association (AUA) and the Endocrine Society (ES) published… read more here.
Keywords: endocrine society; testosterone replacement; american urological; urological association ... See more keywords
Effectiveness of testosterone therapy in hypogonadal patients and its controversial adverse impact on the cardiovascular system
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DOI: 10.1080/10408444.2020.1789944
Abstract: Abstract Testosterone is the major male hormone produced by testicles which are directly associated with man’s appearance and secondary sexual developments. Androgen deficiency starts when the male hormonal level falls from its normal range though,… read more here.
Keywords: replacement therapy; disease; testosterone; testosterone replacement ... See more keywords
Cardiovascular benefits and risks of testosterone replacement: another warning?
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DOI: 10.1093/cvr/cvx143
Abstract: Although testosterone (T) replacement is increasingly being used clinically, cardiovascular benefits and risks of T administration to older men with age-related decline in T levels remain uncertain. The WHI randomized trial reporting potential harmful coronary… read more here.
Keywords: risks testosterone; replacement another; testosterone replacement; cardiovascular benefits ... See more keywords
Effects of testosterone replacement therapy on metabolic syndrome among Japanese hypogonadal men: A subanalysis of a prospective randomised controlled trial (EARTH study)
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DOI: 10.1111/and.12815
Abstract: We investigated the effects of testosterone replacement therapy (TRT) on metabolic factors among hypogonadal men with a metabolic syndrome. From the study population of the EARTH study, which was a randomised controlled study in Japan,… read more here.
Keywords: replacement therapy; hypogonadal men; study; testosterone replacement ... See more keywords
Testosterone therapy preserves muscle strength and power in aging men with type 2 diabetes—a randomized controlled trial
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DOI: 10.1111/andr.12396
Abstract: The purpose of the study was to evaluate whether testosterone replacement therapy improves muscle mechanical and physical function in addition to increasing lean leg mass and total lean body mass in aging men with type… read more here.
Keywords: replacement therapy; mass; testosterone; testosterone replacement ... See more keywords