BMAL1 knockdown promoted apoptosis and reduced testosterone secretion in TM3 Leydig cell line.
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DOI: 10.1016/j.gene.2020.144672
Abstract: Brain and muscle Arnt-like protein-1 (BMAL1) is a clock gene that plays an important role in hormone secretion and apoptosis, but its effect on Leydig cells is unidentified. Here the role of BMAL1 in apoptosis… read more here.
Keywords: secretion; apoptosis; testosterone secretion; leydig ... See more keywords
Activation of Autophagy by Low-Dose Silica Nanoparticles Enhances Testosterone Secretion in Leydig Cells
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DOI: 10.3390/ijms23063104
Abstract: Silica nanoparticles (SNPs) can cause abnormal spermatogenesis in male reproductive toxicity. However, the toxicity and toxicological mechanisms of SNPs in testosterone synthesis and secretion in Leydig cells are not well known. Therefore, this study aimed… read more here.
Keywords: silica nanoparticles; leydig cells; secretion; low doses ... See more keywords