Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.108726
Abstract: Tetrandrine (TET) and cepharanthine (CEP) are two bisbenzylisoquinoline alkaloids isolated from the traditional herbs. Recent molecular investigations firmly supported that TET or CEP would be a potential candidate for cancer chemotherapy. Prognosis of patients with… read more here.
Keywords: cep; tet cep; glucocorticoid resistant; jurkat ... See more keywords
Cepharanthine inhibits enterovirus entry by endolysosomal deacidification and exhibits protective activity in vivo
Sign Up to like & getrecommendations! Published in 2025 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00764-25
Abstract: ABSTRACT Enteroviruses, which belong to the Picornaviridae family, are linked to a range of clinical illnesses that vary from mild to severe, including life-threatening diseases. Among these, enterovirus 71 (EV71) infections in infants and young… read more here.
Keywords: inhibits enterovirus; vivo; cep; tet cep ... See more keywords