Abstract 2226: Modeling the role of Tet-deficiency and restoration in Bcl2-driven B cell lymphoma progression
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DOI: 10.1158/1538-7445.am2023-2226
Abstract: Loss of function in DNA methylation regulators such as the Ten-eleven translocation (TET1-3) proteins, have been implicated in the progression of lymphoma. TET enzymes constitute a family of iron and αKG-dependent dioxygenases that oxidize 5-methylcytosine… read more here.
Keywords: lymphoma progression; tet deficiency; cell lymphoma; progression ... See more keywords