Articles with "tet regulated" as a keyword



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Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells

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Published in 2019 at "Oncoimmunology"

DOI: 10.1080/2162402x.2018.1542917

Abstract: ABSTRACT We explored whether engineering of T cell specificity and effector function improves immunotherapy of solid tumors. Although IL-12 can enhance cancer immunity, a strategy of safe IL-12 delivery without toxicity is currently lacking. We… read more here.

Keywords: expression; regulated expression; cancer; tet regulated ... See more keywords